TESTING THE ANTIBACTERIAL EFFECTIVENESS OF ETHANOL EXTRACTS FROM CHINESE BETEL LEAF (PEPEROMIA PELLUCIDA L.) USING A COMPARISON OF MACERATION AND SOXHLET EXTRACTION METHODS AGAINST STAPHYLOCOCCUS AUREUS AND ESCHERICHIA COLI BACTERIA

Abstrak

Chinese betel leaf known by the Latin name Peperomia pellucida L. is one of the plants that has secondary metabolite compounds that can act as medicinal ingredients that are efficacious to inhibit the growth of bacteria that cause infection. This study aims to determine the antibacterial effectiveness of Chinese betel leaves taken in Aimas, Sorong Regency, Southwest Papua. The bacteria used in this study are Staphylococcus aureus and Escherichia coli bacteria. maceration and sohxletasi with extract concentrations of 12.5%, 25%, 50%. The results showed that Chinese siri leaves at extract concentrations with the maceration method showed effectiveness on S.aureus bacteria with inhibition zones formed at a concentration of 12.5% with a diameter of 5.83 mm, 25% with a diameter of 10 mm, and 50% with a diameter of 12.83 mm. Pada bakteri E. coli ketiga konsentrasi terbentuk zona hambat masing-masing 4,75 mm, 6 mm, 10,83 mm. In contrast to the results of the ethanol extract of Chinese siri leaves with the soxhletation method did not show any inhibition zone on S. aureus and E. coli bacteria. The conclusion in this study is that extra ethanol of Chinese siri leaves using the maceration method has effectiveness against Staphylococcus aureus and Eschericia coli bacteria.