FORMULASI SEDIAAN HAIR TONIC ANTI KETOMBE MINYAK ATSIRI DAUN CENGKEH (SYZYGIUM AROMATICUM L.) DAN UJI AKTIVITAS TERHADAP JAMUR MALASSEZIA FURFUR DENGAN METODE DIFUSI

Abstrak

Minyak atsiri daun cengkeh (Syzygium aromaticum L.) mengandung senyawa eugenol dan kariofilen. Selain itu terdapat senyawa aktif meliputi alkaloid, flavonoid, saponin, tannin, terpenoid/steroid yang berfungsi sebagai antioksidan, antibakteri, dan anti jamur. Minyak atsiri daun cengkeh didapat dari proses destilasi uap air. Hair tonic adalah kosmetik berbentuk cair yang digunakan merawat rambut dan kulit kepala. Penelitian ini bertujuan untuk mengatahui konsentrasi terbaik hair tonic minyak atsiri daun cengkeh yang dapat menghambat pertumbuhan jamur Malassezia furfur penyebab ketombe. Penelitian ini menggunakan metode eksperimental. Minyak atsiri daun cengkeh diuji aktivitas anti jamurnya dengan konsentrasi 20%, 30%, dan 40%. Sediaan hair tonic di evaluasi dengan uji organoleptik, uji ph, uji viskositas, uji homogenitas, aktivitas anti jamurnya terhadap jamur Malassezia furfur dengan metode difusi cakram. Hasil uji evaluasi sediaan sudah memenuhi standar parameter sediaan hair tonic dan pada uji aktivitas anti jamur sediaan hair tonic konsentrasi 20% (12,81 mm), konsentrasi 30% (15,75 mm), konsentrasi 40% (23,81 mm), kontrol negatif (0,26 mm) dan kontrol positif (22,23 mm). Sehingga dapat ditarik kesimpulan konsentrasi terbaik untuk menghambat aktivitas pertumbuh.

Clove leaf essential oil (Syzygium aromaticum L.) contains eugenol and cariophyllene compounds. In addition, there are active compounds including alkaloids, flavonoids, saponins, tannins, terpenoids/steroids that function as antioxidants, antibacterial, and anti-fungal. Clove leaf essential oil is obtained from the water vapor distillation process. Hair tonic is a liquid cosmetic used to treat hair and scalp. This study aims to determine the best concentration of clove leaf essential oil hair tonic that can inhibit the growth of Malassezia furfur fungus that causes dandruff. This study used an experimental method. Clove leaf essential oil was tested for antifungal activity with concentrations of 20%, 30%, and 40%. Hair tonic preparations were evaluated by organoleptical test, ph test, viscosity test, homogeneity test, antifungal activity against Malassezia furfur fungus by disc diffusion method. The results of the preparation evaluation test have met the standard parameters of hair tonic preparations and in the anti-fungal activity test of 20% concentration hair tonic preparations (12.81 mm), 30% concentration (15.75 mm), 40% concentration (23.81 mm), negative control (0.26 mm) and positive control (22.23 mm). So it can be concluded that the best concentration to inhibit the growth activity of Malassezia furfur fungus is 40% with an average inhibition of 23.81 mm.