PENGARUH FREKUENSI DONOR DARAH TERHADAP KADAR KOLESTEROL PENDONOR DI PALANG MERAH INDONESIA (PMI) KOTA SURAKARTA

Abstrak

Cholesterol is an essential component of cell structural membranes and is an important framework for brain and nerve cells and is also a material for the formation of steroids such as folic acid, estrogen, endogenous, prostesterone, adrenal cortex hormones and bile acids. The normal value for cholesterol levels is less than 200 mg/dl. Meanwhile, blood donation is the process of taking blood from someone voluntarily to be stored in a blood bank for later use in blood transfusions. There are several actions that can reduce blood cholesterol levels, one of which is donating blood. Blood donation can control cholesterol levels in the blood because the presence of lipids in blood vessels is reduced and there is a dilution effect. In Indonesia, especially in the city of Surakarta, there has been no research on the effect of donor frequency on blood cholesterol levels, so far there has only been research on the relationship between blood donation and cholesterol levels and so on. The aim of this research is to determine the effect of blood donation frequency on donors' cholesterol levels in PMI Surakarta City. This research method is observational analytical research with a cross sectional approach. The sample in this study consisted of 46 blood donor respondents, namely 30 respondents with a regular donor frequency and 16 respondents with a non-routine donor frequency. The research was carried out using serum samples using the Enzymatic Cholesterol Hydrolysis and Oxidation Determination from Hydrogen Peroxide and Aminophenazone (CHOD-PAP) examination method using the Cobas C111 instrument. The t test shows a 2-tailed sig value of 0.01<0.05 indicating a significant difference between regular and non-routine donors. This shows that there is an influence of the frequency of blood donations on cholesterol levels in donors at PMI Surakarta City